Product Datasheet
UPP2 Antibody
Catalog Number: 40400
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O95045
Gene Accssion:NP_775491
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human uridine phosphorylase 2
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry:1:30-1:150
- other_names:
- UP2; UPASE2; UDRPASE2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total UPP2 protein.
- Background:
- Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
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