Product Datasheet
TRIM22 Antibody
Catalog Number: 40381
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8IYM9
Gene Accssion:NP_006065
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human tripartite motif containing 22
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200
- other_names:
- RNF94; STAF50; GPSTAF50
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRIM22 protein.
- Background:
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
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