Product Datasheet
SSX5 Antibody
Catalog Number: 40374
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O60225
Gene Accssion:NP_066295
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human synovial sarcoma, X breakpoint 5
- appl_detail:
- Western blotting: 1:200-1:1000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SSX5 protein.
- Background:
- The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations.?
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