Product Datasheet  
RNF7 Antibody  
Catalog Number: 40323  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9UBF6
    Gene Accssion:BC005966
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry:1:10-1:50
  • other_names：  
  • SAG; ROC2; CKBBP1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total RNF7 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B).?



 
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