Product Datasheet  
PKM Antibody  
Catalog Number: 40306  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P14618
    Gene Accssion:NP_872270
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human pyruvate kinase, muscle
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Immunohistochemistry:1:25-1:100
  • other_names：  
  • PK3; TCB; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PKM protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.



 
© Signalway Biotechnology All Rights Reserved.