Product Datasheet
NUP98 Antibody
Catalog Number: 40284
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P52948
Gene Accssion:NP_005378
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human nucleoporin 98kDa
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- ADIR2; NUP96; NUP196
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NUP98 protein.
- Background:
- Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC.
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