Product Datasheet
ERP44 Antibody
Catalog Number: 40273
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9BS26
Gene Accssion:NP_055866
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human endoplasmic reticulum protein 44
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry:1:25-1:100
- other_names:
- PDIA10; TXNDC4
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ERP44 protein.
- Background:
- ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor,type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins.
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