Product Datasheet
TNIP1 Antibody
Catalog Number: 40258
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q15025
Gene Accssion:NP_006049
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human TNFAIP3 interacting protein 1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:200
- other_names:
- VAN; NAF1; ABIN-1; nip40-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TNIP1 protein.
- Background:
- This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.?
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