Product Datasheet
TMEFF2 Antibody
Catalog Number: 40252
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9UIK5
Gene Accssion:NP_057276
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human transmembrane protein with EGF-like and two follistatin-like domains 2
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- TR; HPP1; TPEF; TENB2; CT120.2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TMEFF2 protein.
- Background:
- TMEFF2 (transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor¨Clike domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.?
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