Product Datasheet
ABCC8 Antibody
Catalog Number: 40228
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q09428
Gene Accssion:NP_000343
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- HI; SUR; HHF1; MRP8; PHHI; SUR1; ABC36; HRINS; TNDM2; SUR1delta2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ABCC8 protein.
- Background:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release.?
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