Product Datasheet
SPTAN1 Antibody
Catalog Number: 40221
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q13813
Gene Accssion:NP_003118
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human spectrin, alpha, non-erythrocytic 1
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- NEAS; EIEE5; SPTA2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SPTAN1 protein.
- Background:
- Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation.
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