Product Datasheet
LONP1 Antibody
Catalog Number: 40199
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P36776
Gene Accssion:NP_001263408
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human lon peptidase 1, mitochondrial
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry:1:25-1:100
- other_names:
- LON; LONP; PIM1; hLON; LonHS; PRSS15
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LONP1 protein.
- Background:
- This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome.?
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