Product Datasheet
CERS3 Antibody
Catalog Number: 40197
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8IU89
Gene Accssion:NP_849164
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 3
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- ARCI9; LASS3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CERS3 protein.
- Background:
- LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in the production of a 419 amino acid protein (LASS3-long). LASS3 overproduction raises the level of several ceramide species, including C18:0- and C24:0-ceramides.
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