Product Datasheet
BOK(BH3 domain) Antibody
Catalog Number: 40191
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9UMX3
Gene Accssion:NP_115904
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human BCL2-related ovarian killer
- appl_detail:
-
Immunohistochemistry:1:20-1:100
- other_names:
- BOKL; BCL2L9
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total BOK(BH3 domain) protein.
- Background:
- The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.
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