Product Datasheet
HOXD13 Antibody
Catalog Number: 40183
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P35453
Gene Accssion:NP_000514
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human homeobox D13
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- DE; SPD; BDSD; HOX4I
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HOXD13 protein.
- Background:
- This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities.
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