Product Datasheet
EFNB3 Antibody
Catalog Number: 40179
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q15768
Gene Accssion:NP_001397
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ephrin-B3
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- EFL6; EPLG8; LERK8
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EFNB3 protein.
- Background:
- EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats.
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