Product Datasheet
UBAP1 Antibody
Catalog Number: 40173
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9NZ09
Gene Accssion:BC098141
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human ubiquitin associated protein 1
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- UAP; UBAP; NAG20; UBAP-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total UBAP1 protein.
- Background:
- This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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