Product Datasheet
NME8 Antibody
Catalog Number: 40171
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8N427
Gene Accssion:BC036816
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human NME/NM23 family member 8
- other_names:
- CILD6; SPTRX2; TXNDC3; NM23-H8; sptrx-2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NME8 protein.
- Background:
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
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