Product Datasheet
TWIST2 Antibody
Catalog Number: 40170
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8WVJ9
Gene Accssion:BC017907
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human twist family bHLH transcription factor 2
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- FFDD3; DERMO1; SETLSS; bHLHa39
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TWIST2 protein.
- Background:
- The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.
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