Product Datasheet
TRAIP Antibody
Catalog Number: 40169
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9BWF2
Gene Accssion:BC000310
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human TRAF interacting protein
- appl_detail:
-
Immunohistochemistry:1:30-1:150
- other_names:
- TRIP; RNF206
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRAIP protein.
- Background:
- This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
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