Product Datasheet
TRIB3 Antibody
Catalog Number: 40167
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q96RU7
Gene Accssion:BC019363
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- NIPK; SINK; TRB3; SKIP3; C20orf97
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRIB3 protein.
- Background:
- The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
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