Product Datasheet
TKTL1 Antibody
Catalog Number: 40152
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P51854
Gene Accssion:BC025382
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human transketolase-like 1
- appl_detail:
-
Immunohistochemistry:1:30-1:150
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TKTL1 protein.
- Background:
- The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.
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