Product Datasheet
ARMC10 Antibody
Catalog Number: 40125
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8N2F6
Gene Accssion:BC003586
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- other_names:
- SVH; PNAS112; PNAS-112; PSEC0198
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ARMC10 protein.
- Background:
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.?
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