Product Datasheet  
RASGEF1A Antibody  
Catalog Number: 40070  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q8N9B8
    Gene Accssion:BC022548
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to residues near the C terminal of human RasGEF domain family, member 1A
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry:1:20-1:100
  • other_names：  
  • CG4853
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total RASGEF1A protein.
  • Applications：  
  • IHC
  • Background：  
  • RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.?



 
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