Product Datasheet  
Bim Monoclonal Antibody  
Catalog Number: 26025  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O43521
    Gene ID:10018
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year.
  • Immunogen：  
  • Raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Bim (1C2H4): Bcl-2 interacting protein, Bcl-2-related ovarian death gene, BOD, Bcl-2-like 11
  • Purification：  
  • Immunoaffinity chromotography purified IgG
  • Specificity：  
  • Applications：  
  • ELISA WB ICC
  • Background：  
  • Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.



 
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