Product Datasheet  
Histone H2B(acetyl K20) Antibody  
Catalog Number: HW230  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:O60814
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000
    IHC: 1:100-1:500
    ICC: 1:100-1:500

    FC: 1:50-1:100
  • other_names:  
  • H2B 1A antibody
    H2B antibody
    H2B histone family antibody
    H2B2f antibody
    H2B2F_HUMAN antibody
    H2Ba antibody
    H2Bf antibody
    HIST2H2BF antibody
    histone H2B antibody
    histone H2B type 1 antibody
    Histone H2B type 2-F antibody
    MGC131639 antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IHC, IP, FC
  • Background:  
  • Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.



 
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