Product Datasheet
CDH23 antibody
Catalog Number: 38463
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H251
NCBI Gene ID: 64072
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Fusion protein of human CDH23.
- appl_detail:
- WB 1:500 - 1:2000
IHC 1:100 - 1:200
- other_names:
- DFNB12; DKFZp434P2350; FLJ00233; FLJ36499; KIAA1774; KIAA1812; M GC102761; USH1D; CDHR23;
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total CDH23 antibody.
- Background:
- This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
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