Product Datasheet
NEUROG3 antibody
Catalog Number: 38461
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y4Z2
NCBI Gene ID: 50674
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Recombinant protein of human NEUROG3.
- reactivity:
- Human,Mouse,Rat
- other_names:
- ngn3; Atoh5; NGN-3; Math4B; bHLHa7;
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total NEUROG3 antibody.
- Background:
Neurogenin-3 is a protein that in humans is encoded by the NEUROG3 gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix (bHLH) transcription factors involved in the determination of neural precursor cells in the neuroectoderm. The pancreas and brain the major splicing isoform does not code for a protein. Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1.
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