Product Datasheet  
PTPRA antibody  
Catalog Number: 38329  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P18433
    NCBI Gene ID: 5786
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein of human PTPRA.
  • reactivity:  
  • Human,Mouse
  • appl_detail:  
  • WB 1:500 - 1:2000
    IHC 1:100 - 1:200
  • other_names:  
  • LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha;
  • Purification:  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity:  
  • The antibody detects endogenous level of total PTPRA antibody.
  • Applications:  
  • WB,IHC
  • Background:  
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.



 
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