Product Datasheet
APOA1 antibody
Catalog Number: 38197
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P02647
NCBI Gene ID: 335
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Recombinant protein of human APOA1.
- appl_detail:
- WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
- other_names:
- APOA1;MGC117399;Apo-AI;ApoA-I;APOAI
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total APOA1 antibody.
- Background:
- ApoAI (Apolipoprotein A1) is a major component of high density lipoprotein (HDL, the ¡°good cholesterol¡±) in plasma. It is produced in the liver and small intestine. ApoA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) that is responsible for the formation of plasma cholesteryl esters and promotes cholesterol efflux from tissues to the liver for excretion. Defects in ApoA1 are associated with high density lipoprotein deficiency (HDLD) and systemic non-neuropathic amyloidosis (1-3).
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