Product Datasheet  
Cyclooxygenase 2 Rabbit Polyclonal Antibody  
Catalog Number: 38024  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P35354
  • Form of Antibody：  
  • IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:1000

  • other_names：  
  • Prostaglandin G/H synthase 2;PHS II;PTGS2
  • Purification：  
  • Affinity purification using immunogen.
  • Specificity：  
  • The COX2 Rabbit Polyclonal antibody detects endogenouse COX2 proteins..
  • Applications：  
  • WB
  • Background：  

  • Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.




 
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