Product Datasheet
SLIT1 Antibody
Catalog Number: 37950
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75093
NCBI Gene ID: 6585
Gene Accssion: NP_003052/O75093
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human slit homolog 1 (Drosophila)
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MEGF4; SLIL1; SLIT3; SLIT-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLIT1 protein.
- Background:
- Slit homolog 1 protein?is a?protein?that in humans is encoded by the?SLIT1?gene. Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions By similarity. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
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