Product Datasheet
SLC13A3 Antibody
Catalog Number: 37949
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8WWT9
NCBI Gene ID: 64849
Gene Accssion: NP_073740/Q8WWT9
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- NADC3; SDCT2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLC13A3 protein.
- Background:
- Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.?
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