Product Datasheet
SLC34A3 Antibody
Catalog Number: 37940
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N130
NCBI Gene ID: 142680
Gene Accssion: NP_001170787/Q8N130
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 34 (type II sodium/phosphate contransporter), member 3
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- HHRH; NPTIIc
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLC34A3 protein.
- Background:
- This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.
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