Product Datasheet
SIGLEC15 Antibody
Catalog Number: 37925
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6ZMC9
NCBI Gene ID: 284266
Gene Accssion: NP_998767/Q6ZMC9
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human SIGLEC15
- appl_detail:
- Western blotting: 1:500-1:2000
Immunofluorescence: 1:50-1:200
- other_names:
- CD33L3; HsT1361; SIGLEC-15
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SIGLEC15 protein.
- Background:
Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.
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