Product Datasheet  
SIGLEC8 Antibody  
Catalog Number: 37922  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9NYZ4
    NCBI Gene ID: 27181
    Gene Accssion: NP_055257/Q9NYZ4
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human sialic acid binding Ig-like lectin 8
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:25-1:100

    WB dilution: 1:500-1:2000

    IHC dilution: 1:50-1:200

  • other_names：  
  • SAF2; SIGLEC-8; SIGLEC8L
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total SIGLEC8 protein.
  • Applications：  
  • WB IHC
  • Background：  

  • Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein.




 
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