Product Datasheet
SERPING1 Antibody
Catalog Number: 37916
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P05155
NCBI Gene ID: 710
Gene Accssion: NP_000053/P05155
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- C1IN; C1NH; HAE1; HAE2; C1INH
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SERPING1 protein.
- Background:
- This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
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