Product Datasheet
SERINC3 Antibody
Catalog Number: 37913
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13530
NCBI Gene ID: 10955
Gene Accssion: NP_006802/Q13530
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human serine incorporator 3
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- TDE; TDE1; AIGP1; TMS-1; DIFF33; SBBI99
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SERINC3 protein.
- Background:
- TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue.?
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