Product Datasheet  
SASH1 Antibody  
Catalog Number: 37895  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O94885
    NCBI Gene ID: 23328
    Gene Accssion: NP_056093/O94885
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human SAM and SH3 domain containing 1
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • SH3D6A; dJ323M4; dJ323M4.1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total SASH1 protein.
  • Applications：  
  • IHC
  • Background：  
  • SASH1 (SAM and SH3 domain-containing protein 1), also known as PEPE1 (Proline-glutamate repeat-containing protein), is a 1247 amino acid protein that is significantly downregulated in the majority of primary breast tumor tissues, breast cancer cell lines, lung and thyroid tumors, as well as in certain colon carcinomas. It has been hypothesized that its expression is suppressed not due to mutation of the SASH1 gene, but instead via other mechanisms, such as promoter methylation.



 
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