Product Datasheet
TRIM3 Antibody
Catalog Number: 37876
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75382
NCBI Gene ID: 10612
Gene Accssion: NP_001234935/O75382
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human tripartite motif containing 3
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- BERP; HAC1; RNF22; RNF97
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRIM3 protein.
- Background:
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4.?
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