Product Datasheet
KDM5A Antibody
Catalog Number: 37863
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P29375
NCBI Gene ID: 5927
Gene Accssion: NP_001036068/P29375
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 5A
- other_names:
- RBP2; RBBP2; RBBP-2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KDM5A protein.
- Background:
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
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