Product Datasheet
POU6F2 Antibody
Catalog Number: 37841
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P78424
NCBI Gene ID: 11281
Gene Accssion: NP_001159490/P78424
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human POU class 6 homeobox 2
- other_names:
- WT5; WTSL; RPF-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total POU6F2 protein.
- Background:
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition.?
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