Product Datasheet
PON1 Antibody
Catalog Number: 37840
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P27169
NCBI Gene ID: 5444
Gene Accssion: NP_000437/P27169
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human paraoxonase 1
- appl_detail:
- Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200
- other_names:
- ESA; PON; MVCD5
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PON1 protein.
- Background:
- The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
© Signalway Biotechnology All Rights Reserved.