Product Datasheet  
PLEC Antibody  
Catalog Number: 37832  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q15149
    NCBI Gene ID: 5339
    Gene Accssion: NP_000436/Q15149
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from internal residues of human plectin
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:50-1:200
  • other_names:  
  • HD1; PCN; EBS1; EBSO; PLTN; PLEC1; LGMD2Q; PLEC1b
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total PLEC protein.
  • Applications:  
  • IHC
  • Background:  
  • Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes.



 
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