Product Datasheet  
PGLYRP1 Antibody  
Catalog Number: 37820  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O75594
    NCBI Gene ID: 8993
    Gene Accssion: NP_005082
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human peptidoglycan recognition protein 1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:200-1:1000
  • other_names：  
  • PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PGLYRP1 protein.
  • Applications：  
  • WB
  • Background：  
  • Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-I? and PGRP-I¡Ò are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.



 
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