Product Datasheet  
PDE4A Antibody  
Catalog Number: 37809  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P27815
    NCBI Gene ID: 5141
    Gene Accssion: NP_001104777/P27815
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human phosphodiesterase 4A, cAMP-specific
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • PDE4; DPDE2; PDE46
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PDE4A protein.
  • Applications：  
  • WB IHC
  • Background：  
  • The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.



 
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