Product Datasheet
FGF3 Antibody
Catalog Number: 36771
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P11487
NCBI Gene ID: 2248
Gene Accssion: NP_005238
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human fibroblast growth factor 3
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- INT2; HBGF-3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FGF3 protein.
- Background:
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
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