Product Datasheet
ICOSLG Antibody
Catalog Number: 36767
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75144
NCBI Gene ID: 23308
Gene Accssion: NP_056074/O75144
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human inducible T-cell co-stimulator ligand
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ICOSLG protein.
- Background:
- ICOS ligand?is a?protein?that in humans is encoded by the?ICOSLG?gene. ICOSLG has also been designated as CD275 (cluster of differentiation 275). Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
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