Product Datasheet
PPP1R13B Antibody
Catalog Number: 36764
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96KQ4
NCBI Gene ID: 23368
Gene Accssion: NP_056131.1
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Apoptosis-stimulating of p53 protein 1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- PPP1R13B; KIAA0771; p53BP2-like; p85
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PPP1R13B protein.
- Background:
- The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53.Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.
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