Product Datasheet
AATK Antibody
Catalog Number: 36721
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q6ZMQ8
NCBI Gene ID: 9625
Gene Accssion: NP_001073864
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human Apoptosis-associated tyrosine kinase
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- LMR1; AATYK; LMTK1; p35BP; AATYK1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AATK protein.
- Background:
- The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene.
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